Agammaglobulinemia and Staphylococcus aureus botryomycosis in a cohort of related sentinel Swiss Webster mice.

نویسندگان

  • Erin C Bridgeford
  • James G Fox
  • Prashant R Nambiar
  • Arlin B Rogers
چکیده

Sentinel mouse seroconversion to infectious agents is critical for laboratory animal facility disease monitoring. We report spontaneous emergence of non-sex-linked agammaglobulinemia with B-cell deficiency and cutaneous Staphylococcus aureus granulomatosis (botryomycosis) in a cohort of related Swiss Webster sentinel mice. Our experience reinforces the importance of immunocompetency validation in surveillance programs.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 46 5  شماره 

صفحات  -

تاریخ انتشار 2008